YETİŞKENLERDE TAS1R2 TAT RESEPTÖR POLİMORFİZMİNİN BESİN SEÇİMİ VE KARBONHİDRAT ALIMINA ETKİSİ

Abstract

Taste perception plays a key role in discovering individual food preferences and dietary habits. Sweet taste is an influential factor that affect food intake in particular. Various food choices are influenced by hedonic systems, various motivations and traits. The factors that play a role in the food choice and consumption process are not completely known yet. In our study, we aimed to investigate the effect of SNP rs35874116 polymorphism in the sweet taste receptor (TAS1R2) gene on food choice and carbohydrate intake. In this study, a total of 95 volunteers, 65 women and 30 men were included. Demographic data of the individuals was recorded, food choice test and hedonistic eating scale questionnaires were fill down by the individuals and food consumption records were taken. Venous blood samples were collected from each individual to determine their genotype distribution. Genotype distributions were determined in the isolated DNA samples by using the competitive allele specific PCR method. When the participants were examined by genotype and allele frequencies, the rate of individuals with the GA genotype was 67,3%, the rate of individuals with the AA genotype was 26,3%, and the rate of individuals with the GG genotype was 6,3%. In our study, when the relationship between TAS1R2 sweet taste receptor genotype distribution and carbohydrate intake and food choice motivation were evaluated; It was determined that there was a statically significant negative weak relationship (p <0,05) between carbohydrate intake of 64 individuals with the GA genotype and health (rs = -, 314, p = 0.011) and weight control (rs = -, 315, p = 0.011) motivations. It was found that there was a statistically significant negative and very strong correlation (p <0.05) between the sucrose intake of individuals with the GG genotype and familiarity with the sub-dimensions of the food choice test (r = -, 943, p = 0.005). However, there was no statistically significant difference between hedonistic eating scores and food xii selection motivations according to genotypes (p> 0.05). Although the amount of carbohydrate and sucrose consumption of individuals with GG genotype was high compared to other genotypes, no statistically significant difference was found. In our study, it was determined that the highest motivation for food selection in individuals was sensory appearance, and the least important motivation is ethical concerns. It was determined that women attach more importance to motivation of health, fitness and weight control food choice than men and this relationship is statistically significant (p <0.05). In our study, the effect of polymorphism in the sweet taste receptor (TAS1R2) gene on carbohydrate and sucrose intake of individuals was not directly determined. Although it was concluded that genetic variations may have an impact on food choices, nutrient consumption, and hedonistic eating, more work is needed with broader groups to illuminate the impact of genetic variants on our eating habits.