PROLIFERATIVE VERRUCOUS LEUKOPLAKIA: FIVE YEARS FOLLOW-UP

Abstract

Background: Proliferative verrucous leukoplakia (PVL) is the rarest and stubborn subtype of oral leukoplakia (OL). The origin of PVL is still unknown and because the possible risk factors of OL are not in complete accordance with PVL, diagnosing the disease is very hard. PVL also needs special attention because of the high progression rate of squamous cell carcinoma and verrucous carcinoma. Case Report: A 54 year old female patient was admitted to our department with the complaint of painless white lesions in anterior region of the floor of the mouth. In the light of the clinical and radiological findings, with the initial OL diagnosis, lesion was excised using electrocautery as a whole under local anesthesia and sent for histopathological examination. Final diagnosis was “Proliferative Verrucous Hyperplasia”. After 60 months of follow-up, there was no recurrence. Conclusion and Clinical Relevance: Since PVL has high progression rate for malign lesions and high relapse rates, it is important to detect the disease at early stages, and long term follow-up after surgical excision is needed